New research confirms what many suspect: chronic insomnia combined with obstructive sleep apnea (COMISA) dramatically increases the likelihood of developing cardiovascular disease. A landmark study following nearly one million U.S. veterans over two decades reveals that individuals suffering from both conditions face over three times the risk compared to those with neither. This isn’t just about feeling tired; it’s a serious threat to long-term heart health.
What is COMISA? A Dangerous Combination
COMISA represents the coexistence of insomnia – difficulty falling or staying asleep – and obstructive sleep apnea, where breathing repeatedly stops and starts during sleep. These are the two most prevalent sleep disorders, often occurring together. Roughly 14% of the study participants experienced both simultaneously, highlighting how frequently these conditions overlap.
This is critical because the combined effect is far worse than either disorder alone. While both insomnia and sleep apnea independently elevate cardiovascular risk, their presence together creates a synergistic effect, accelerating damage to the heart.
Key Findings from the Veteran Study
Researchers tracked 984,946 veterans for up to 20 years, comparing outcomes across different sleep disorder groups. The results were stark:
- Hypertension Risk: COMISA was linked to a more than two-fold increase in the development of high blood pressure.
- Cardiovascular Disease Risk: Individuals with COMISA faced over a three-fold higher risk of heart disease.
- Gender Consistency: These associations remained consistent across both male and female participants.
These findings underscore that ignoring sleep problems isn’t merely about discomfort; it’s about neglecting a major cardiovascular risk factor.
Why Disrupted Sleep Harms the Heart
Healthy sleep allows the cardiovascular system to rest and repair, with heart rate and blood pressure naturally dipping. Fragmented or disrupted sleep prevents this essential recovery. Sleep apnea causes intermittent oxygen deprivation, stressing the heart and blood vessels. Insomnia keeps the body in a state of chronic alertness, triggering inflammation and sustained stress responses. Together, they create a “perfect storm” of cardiovascular strain.
This is why treating these conditions is vital, not just for energy levels, but for the sake of long-term cardiac health.
Signs You Might Have COMISA
Recognizing the signs of COMISA is the first step toward seeking help:
- Difficulty falling or staying asleep, despite consistent sleep hygiene.
- Loud snoring or observed breathing pauses during sleep (reported by a partner).
- Waking up gasping for air or with a dry mouth.
- Excessive daytime fatigue, even after adequate time in bed.
Many people with sleep apnea are unaware they have it, making awareness crucial. If your sleep feels persistently broken despite your best efforts, it’s time to investigate.
What to Do About It
The first step is talking to your doctor about a sleep study, the only definitive diagnostic method for sleep apnea. Treatment for insomnia often involves cognitive behavioral therapy (CBT-I). Sleep apnea can be managed with therapies like continuous positive airway pressure (CPAP) or other interventions to keep airways open during sleep.
Researchers now recommend evaluating sleep as routinely as other major cardiovascular risk factors, such as blood pressure and cholesterol. The good news is that these conditions are treatable, but only with proper diagnosis and intervention.
The bottom line: COMISA represents a significant, yet manageable, risk to cardiovascular health. Prioritizing sleep is not a luxury; it’s an essential component of long-term heart protection. If symptoms resonate, discuss a sleep study with your doctor.




















